Pilonidal disease was first described by Hodges in 1880  and is diagnosed by the finding of a characteristic epithelial track (the sinus) situated in the skin of the natal cleft, a short distance behind the anus and generally containing hair, hence the name pilonidal taken from the Latin, meaning literally ‘nest of hairs’. During the Second World War the condition was common in jeep drivers, which led to it being known as ‘jeep disease’. A similar condition arises in the clefts between the fingers of barbers or hairdressers caused by customers’ hair entering moist, damaged skin.
The onset of PNS is rare both before puberty and after the age of 40. Males are affected more frequently than females, probably due to their more hirsute nature . In a population study of 50,000 students the incidence in males was 1.1%, ten times more than in females , although many of these were asymptomatic. Figures from the Office of Population Censuses and Surveys (1985) record 7,000 patients as having had inpatient treatment for PNS in England. Proportionately females make up a quarter of those undergoing hospital treatments , possibly reflecting under-reporting in the male population. The condition is more common in Caucasians than Asians or Africans due to differing hair characteristics and growth patterns . In a study of risk factors the following associations were found :
- sedentary occupation 44%
- positive family history 38%
- obesity 50%
- local irritation or trauma prior to onset of symptoms 34%.
The origin of pilonidal disease is not fully understood, but the majority of opinion favours the acquired theory, which may be summed up as:
Sex hormones first produced at puberty are known to affect the pilosebaceous glands, which coincides with the earliest onset of pilonidal disease . Pilonidal disease is associated with visible pits in the midline of the natal cleft, which have the microscopic appearance of enlarged hair follicles.
The enlargement is thought to occur due to stretching of the follicular openings caused by the weight of the buttocks being pulled by gravity. The magnitude of this force is enhanced by its application over a small area (approximately 1mm²),
where the natal cleft curves over the sharp angle at the sacro-coccygeal joint. This force may be amplified by activities such as bouncing while upright, slumping while seated or bouncing on a hard seat as in ‘jeep disease’. If the force applied reaches a critical level then the base of the follicle ruptures as this is the weakest part at which the skin is tethered to the subcutaneous tissue. The same forces,
together with friction between the buttocks, are also responsible for sucking keratin and hair into the distended follicles, which leads to infection of the follicle and abscess formation.
It had long been believed that hair follicles alone were the source of pilonidal disease. However, more recent work on specimens following wide excision has shown that the pits penetrating into the dermis were distended with keratin and debris, but not all arose in hair follicles.
Furthermore, hair entry to the follicles by a variety of means was originally thought to be the primary event in the development of PNS. However, there is evidence to suggest that the enlargement of the follicles precedes hair gaining access and at operation hair is found in only half of cases.
Hair acts as a foreign body causing an inflammatory reaction and can lead to prolonged inflammation and the development of chronic pilonidal disease. As such, the hairs that gave pilonidal disease its name may not be the primary insult but nonetheless are an important secondary event.
The source of hair can be either the natal cleft itself in hirsute individuals, or hair from the head or back that falls down inside clothes into the natal cleft.
Distension of the obstructed follicle leads to oedema and inflammation resulting in occlusion of the mouth of the pit, with subsequent infection and abscess formation in the subcutaneous fatty tissue (the patient may present at this stage). Over time a chronic abscess develops and it is the formation of the track draining this abscess cavity that is known as a sinus.
The combination of a deep abscess cavity with surrounding moist conditions and abundant bacteria, hair, debris and friction cause recurrent infection, associated with chronic pain and discharge.
Malignant change is a relatively rare complication of pilonidal disease, but evidence of at least 50 such cases is available in published medical literature. The most common scenario is of squamous cell carcinoma arising after decades of antecedent pilonidal disease. Its pathophysiology is uncertain, but the ongoing processes of tissue damage and repair in the presence of chronic inflammation may be implicated.
Malignancy arising in a chronic wound seems to have a worse prognosis than cutaneous malignancies arising de novo on the skin, hence early detection is imperative.
Although malignancy is a rare complication, it is a significant risk to young men and a more sinister reason why, besides discomfort and inconvenience, pilonidal disease should be taken seriously and sufferers encouraged to seek medical help.
Anaerobic bacteria (particularly Bacteroides and Enterococci) predominate over aerobic bacteria (Staphylococci and Haemolytic Streptococci) in the development of infection of the follicles and abscess formation. Anaerobes are predominantly responsible for reinfection and subsequent wound breakdown following surgery. However a more recent prospective study of 49 infected postoperative wounds isolated aerobic bacteria in 43% of cases. Treatment of pilonidal infection should be with broad spectrum antibiotics.
A PNS may be asymptomatic for some time prior to presentation. The majority of patients only present with the onset of symptoms, usually pain and discharge. Occasionally a painless lump or swelling may be discovered by the patient while washing, or the characteristic midline pits may be found during a routine physical examination. Symptomatic disease usually presents as an acute pilonidal abscess, a chronic pilonidal abscess or complex/recurrent pilonidal disease.
Acute pilonidal abscess
The patient notices increasing discomfort and swelling over a number of days and the pain may be severe by the time of presentation. On examination there is a localised fluctuant swelling in the midline of the natal cleft with overlying cellulitis. The area is exquisitely painful to touch and often simply the act of separating the buttocks to examine the area is intolerable for the patient.
Chronic pilonidal disease
It is common for patients to present with chronic pain and discharge, often with a history of up to two years. On examination a single, or occasionally, multiple sinuses may be seen. Tufts of hair or other debris, such as clothing fibres, are often visible arising from the sinus. Localised oedema, swelling and inflammation may be present masking the underlying sinus.
Complex or recurrent pilonidal disease
This is due to reinfection in neighbouring hair follicles or chronic infection from entry of hair or debris into a postoperative wound.
This will depend upon the nature of presentation and the attitude and wishes of the individual concerned. Regardless of the treatment selected, the aims remain similar:
Treatment must be acceptable to the patient in terms of discomfort, impact upon body image and self-esteem. PILONIDAL SINUS TREATMENT IN KAROL BAGH
Rates of complication and recurrence should be minimal
To enable the patient to resume work and normal social activities as early as possible.
The principle management techniques will be discussed below.
Management of asymptomatic PNS
For those patients who are truly asymptomatic, meticulous depilation and local hygiene are advised. It is not known what proportion of those who are asymptomatic go on to develop symptomatic disease.
However, the risks and discomfort of elective surgery for most of these patients would be unacceptable and probably outweigh the potential benefit of avoidance of future abscess formation. Hence surgical intervention in this group is not advised.
For the acute abscess that presents early, with pain that is tolerable and no evidence of cellulitis, broad spectrum antibiotics and depilation alone may be sufficient to resolve the immediate problem.
If symptoms resolve, follow-up examination for the presence of pits or sinus tracks is recommended along with long-term depilation and attention to hygiene.
The majority of acute cases do, however, require urgent operative intervention. When pain is severe or cellulitis is present, attempts at conservative treatment are likely to be futile and will only prolong the patient’s discomfort.
Chronic disease can be successfully treated by shaving and meticulous hygiene, but recurrence rates are unknown. PILONIDAL SINUS TREATMENT IN FARIDABAD
This is a closed technique under local anaesthetic whereby injection of phenol into a sinus causes sclerosis and gradual closure. The procedure is time consuming, needs frequent repetition, has a high recurrence rate and has been largely replaced by operative techniques.
The number and variety of published techniques are testament to the complexity of treating PNS and the fact that no single procedure is superior in all respects. It is universally agreed that the most effective emergency management of a pilonidal abscess is simple incision and drainage.
However, surgical management of chronic and recurrent disease is more controversial. Numerous studies have been put forward advocating one treatment over another, but many of these studies are weighed down by lack of control groups or short follow-up. The majority of procedures can be classified in one of the four categories below:
- Incision and drainage
- The Excision and healing by secondary intention
- Excision and primary closure
- Excision with reconstructive flap techniques.
Incision and drainage: This is a simple procedure that involves making an elliptical incision in the abscess just off the midline. The mouth of the wound should be of sufficient width to allow packing of the entire wound cavity.
Curettage to remove dead or infected tissue in the wound improves the rate of healing, with 90% completely healed at one month, compared to just 58% healed at 10 weeks in the absence of curettage.
Following a single incision and drainage procedure, 40-60% will go on to develop a PNS requiring further surgery. Pits or sinuses can be excised as part of an incision and drainage procedure, but these can be obscured by oedema and are often overlooked at the initial assessment.
The recurrence rate can be reduced to about 15% if a second procedure to excise pits and sinuses is performed after five to seven days.
Healing by secondary intention has the advantage of allowing free drainage of infected material and debris. However the patient will require regular wound care and the discomfort of packing until the wound has closed. In a retrospective study mean number of days off work following incision and drainage was 20.
Wide excision and healing by secondary intention: Wide excision of an elliptical wedge of skin and subcutaneous tissue down to the pre-sacral fascia is designed to remove all the inflamed tissue and debris allowing the wound to granulate from its base. The excised dimensions should be of sufficient width at both the mouth and base of the wound to allow packing with ease.
The base itself should be relatively flat and of almost comparable size to the mouth of the wound. A narrow V-shaped wound without a flat base is more difficult to pack and has a tendency to bridging and subsequent infection. The procedure necessitates general anesthesia and hospital stay for a few days postoperatively.
The principal advantage is a low recurrence rate but the downside is a lengthy healing time (8-10 weeks) and high direct and indirect costs associated with inpatient care, follow-up wound care, and days lost from work.
PILONIDAL SINUS TREATMENT IN FARIDABAD
Despite this, there is a role for wide excision in those with extensive chronic disease and following failed primary closure surgical technique. Figures 1a-e show different stages in the healing of chronic disease in a young male treated by wide excision.PILONIDAL SINUS TREATMENT IN FARIDABAD